“OSTEOGROW - Novel Bone Morphogenetic Protein 6-Biocompatible Carrier Device for Bone Regeneration“



FP7 – HEALTH - Collaborative project (Contract Number: 279239)


54 months (01/01/2012 - 30/06/2016)


Zagreb, Croatia

Project funding

5.683.089,30 €

Project goals

Production, preclinical and clinical testing of the new drug OSTEOGROW for bone regeneration to accelerate healing of bone defects. OSTEOGROW is a new drug (new bone implant) that consists of the autologous carrier of the patient's own blood and biologically active recombinant human protein BMP6 (rhBMP6) with improved properties in bone regeneration compared to currently available options.

Project results

Production of recombinant BMP6 for the purposes of clinical testing of the drug in Phase I/II; Drug testing OSTEOGROW in two Phase I/II clinical studies; Successfully completed international Phase I/II clinical trials in three clinical centres for two indications: i) healing of distal radius fractures (n = 32 patients) and ii) high tibial osteotomy (n = 20).

Read more

Novel Bone Morphogenetic Protein-6 Biocompatible Carrier Device for Bone Regeneration

Supported by

Eu commision logo
Eu elbem